Saturday, November 28, 2009

Can a diabetic patient be given an ACE inhibitor even though her serum Creatinine is gt; 2.5? -

The patient s Cr is 2.9. Besides nephropathy, she s got retinopathy and hypertension, and has had a BKA twice.

Yes. In most cases, prescribing an ACEI (or ARII blocker) is helpful in slowing the rate of progression of renal insufficiency in diabetics. As with any medication, there are risks involved - the most important things to watch for are in the blood biochemistry - serum potassium can rise sufficiently to require stopping or cutting back on the ACEI, and there may be a worsening in renal function. In general though, the decline in renal function (ie, increase in serum creatinine) is small and non-progressive, allowing the drug to be continued, with good results. So: Yes they can, and often are Drawbacks with high potassium or worsening of renal function are easily spotted and dealt with.

ACE inhibitors are used to treat HBP and Diabetes. That s what they were made for. Ask your doctor about Liprinosil. It treats those two conditions in addition to heart failure.

My MD took me off them even though many recommend ACE inhibitors. My kidney (I only have 1 left) was doing poorly on ACE inhibitor. With her kidneys that hammered she may be spilling potassium and that will give hypertension. Potassium works better for me than the meds. A good book re diabetes is creatinine was helped by 300mg Q10 daily. LEF.org was where I found the info re Q10 They say patients are avoiding dialysis with it. They are a good website. Been around for decades. Build muscle. I think glucose tolerance is affected a lot by inadequate muscle mass. Kind of hard to do without legs though. Do what you can.

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