St Johns Wort can be effective in treating mild depression as hypericin, one of the active ingredients, effects the neurotransmitters in the brain in a similar fashion to anti-depressant meds. However there is a risk of hypertension being caused by St Johns Wort because hypericin can have a reaction when mixed with the amino acid tyramine. Reactions include a quick increase in blood pressure, nasty headaches and an irregular heartbeat. Although these reactions aren t that common its not really worth the risk. However, should you choose to take St Johns Wort then best to avoid foods and drinks that have high concentrations of tyramine. These include: - Aged, dried, smoked, pickled or processed fish or meats - Chicken liver - Aged cheese - Soy sauce - Yeast/protein extracts - Legumes - Over-ripe fruit - Figs or raisins - Alcoholic beverages including ale, beer, red wines, sherry and liqueurs. And its also advisable to limit caffeine. It s not just the risk of reaction from tyarime either that you should be aware of. Like all herbs, just because its natural doesn t mean there can t be side effects. There is a risk that St Johns Wort may interact with other medications, including those for controlling high blood pressure and prescription anti-depressants. So if you re already taking blood pressure meds and anti-depressants of any kind then don t self-medicate with St Johns Wort. If you re interested in alternative remedies you should speak to your doctor about which alternative remedies can address any feelings of mild depression without increasing the risk of high blood pressure.
St. John s wort may cause increased sensitivity to sunlight. Other side effects can include anxiety, dry mouth, dizziness, gastrointestinal symptoms, fatigue, headache, or sexual dysfunction. Research shows that St. John s wort interacts with some drugs. The herb affects the way the body processes or breaks down many drugs; in some cases, it may speed or slow a drug s breakdown. Drugs that can be affected include: Indinavir and possibly other drugs used to control HIV infection Irinotecan and possibly other drugs used to treat cancer Cyclosporine, which prevents the body from rejecting transplanted organs Digoxin, which strengthens heart muscle contractions Warfarin and related anticoagulants Birth control pills Antidepressants When combined with certain antidepressants, St. John s wort may increase side effects such as nausea, anxiety, headache, and confusion. St. John s wort is not a proven therapy for depression. If depression is not adequately treated, it can become severe. Anyone who may have depression should see a health care provider. There are effective proven therapies available. It is important to inform your health care providers about any herb or dietary supplement you are using, including St. John s wort. This helps to ensure safe and coordinated care
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