Wednesday, April 21, 2010

Is there any other treatment for pulmonary hypertension? -

I assume you are talking about Primary pulmonary hypertension. The vessel lining cells and smooth muscles cells which age fail to be recycled, resulting in thickened hard blood vessels leading to the high pressures in the pulmonary vessels. The definitive treatment for primary pulmonary hypertension is lung transplant but the symptoms progression can be slowed by certain drugs which serve to dilate the vessels leading into lungs, through different mechanisms eg. Bosetan (recently approved) serves to dilate the pulmonary vessels and decrease the muscular proliferation. Others like like Epoprostenol serve to dilate through a different mechanism. Secondary pulmonary hypertension has many causes like chronic lung diseases, recurrent small clots in lungs, late congenital heart disease, valvular heart diseases, heart failure, HIV, cirrhosis and others. For these treating the cause will slow progression. Only transplant is curative.

cardio-pulmonary transplant

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