Saturday, March 13, 2010

Can disseminated intravascular coagulation occur as a result of systemic hypertension? -

The comment above about hypertension being man-made is wrong. The use of the word quot;placeboquot; is inappropriate. A placebo is a pill with no medicine in it, used in a scientific study in order to see the difference between when people take the medicine and when they don t - without knowing. Hypertension can be caused by several treatable conditions (such as poor blood flow to a kidney or a tumor that gives off hormones that increase blood pressure) or it can be termed quot;essential hypertensionquot; meaning that there is no identifiable reason that the blood pressure is high. High blood pressure damages organs and shortens life if not controlled. It runs in families and is more common in some ethnic groups than in others. In short, it is a very real physiologic problem that clearly has a genetic contributing cause. Disseminated intravascular coagulation (DIC) is a disasterous complication of critical illness. In patients who have major trauma or severe life threatening infection, a complex process of system-wide inflammation can occur which compromises or destroys the function of multiple organ systems. This is called multiple system organ failure and is frequently fatal. One of the associated phenomena that can happen during this type of severe situation is DIC. In DIC, microscopic clots begin to form within the blood stream, often in tiny blood vessels. The process happens throughout the body which is why it is termed quot;disseminatedquot; as opposed to localized. This process rapidly depletes the clotting factors in the blood and uses up platelets which are tiny cells critical for clot formation. The result of this depletion of clotting supplies is that the patient develops bleeding problems. DIC is not a result of hypertension. Typically it occurs in patients who are critically ill (in the ICU, on a ventilator, hanging on to life by a thread) or who are rapidly becoming critically ill. Although there are numerous possible causes, they all have to do with either major injury or infection, or a related biochemical insult to the system. An example of a non-trauma, non-infectious issue that can involve DIC and hypertension involves a complex of multiple problems related to pregnancy called quot;HELLP syndromequot; (Hemolysis, Elevated Liver enzymes, Low Platelets) which can occur in the setting of quot;pre-eclampsiaquot; or quot;eclampsiaquot;. This too, however, is a process that includes critical illness and systemic inflammation, organ failures and DIC. ...Hope that helps.

DIC in sepsis is due to the bacteria. In trauma, it is the release of damaged itssue into the blood. In pregnancy, it s an accident which leaks amniotic fluid into the maternal blood stream. Hypertension causes chronic injury to vessels with wall thickening, which is a different quot;injuryquot;. Report Abuse

No,it only occurs after you had a few shots of Ronrico 151

hypertension is man made. not medical. a placebo, if you will. you cannot talk yourself into intravascular coagulation any more than you can talk yourself into forming cancer cells. its just not possible.

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